A review on plants possesses anti tubercular activity

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Review Article

Author Details : Pratiksha Patil, Sneha Joshi, Anil Kumar Prajapati*

Volume : 9, Issue : 2, Year : 2023

Article Page : 50-56

https://doi.org/10.18231/j.jpmhh.2023.012

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Abstract

Introduction: Tuberculosis is an infectious disease condition that mainly affects the lungs, and the responsible bacteria is . Over 4,000 people each day die from this disease, which also claims 1.2–1.5 million lives annually and has infected 1.7–2 billion individuals globally.
Materials and Methods: The literature review was conducted by studying the research papers and review articles concentrating on the traditional plants having “Antituberculosis activity or anti-mycobacterial activity”, in electronic databases like PubMed, Science Direct, Scopus, and Google Scholar.
Results: The available synthetic therapy for tuberculosis treatment includes first-line treatment of five drugs namely “Isoniazid, Rifampicin, Ethambutol, Pyrazinamide, and Streptomycin. The synthetic drugs used in the treatment of tuberculosis result in hepatotoxicity and also cause resistance against bacteria, resulting in MDR TB and XDR TB. Plant-derived drugs have potent activity against tuberculosis bacteria also they give hepatoprotective activity, unlike the synthetic drugs with no resistance against the bacteria.
Conclusion: Medicinal plant products are good alternatives to allopathic medicine with fewer side effects and with less chances of resistance. Because polyherbal formulation act by different mechanisms to inhibit the growth of bacteria. More research is required to explore the plant-based treatment of TB.

Keywords: Tuberculosis, Antitubercular, Medicinal Plant for Tb, Herbal drug for Tuberculosis

How to cite : Patil P, Joshi S, Prajapati A K, A review on plants possesses anti tubercular activity. J Prev Med Holist Health 2023;9(2):50-56

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